Surgical clips and implants - formal edition (English)


This folder is based on 34 research papers about surgical clips and implants. It lists known issues and complications.

It is in English and is of a formal style: In wording, it stays as close to the research papers as possible, often directly quoting from them.

If you're looking for a folder that is a bit more readable for someone without medical background, please take a look at the informal version of this folder. The informal versions are pink instead of blue.

Scroll down on the product page to see the full list of papers.

The folder is printed on 170 grams paper and is triple folded. When folded closed its size is A5.

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This folder is based on the following research papers

[1] Benatiya, M., El Kiassi, A., & Rais, G. (2018). Uncommon Case of Ureteral Clip Migration Following Laproscopic Hysterctomy. Journal Of Medical Cases, 9(8), 270-272. doi:10.14740/jmc3114w 

[2] Rou WS, Joo JS, Kang SH, Moon HS, Kim SH, Sung JK, Lee BS, Lee ES.   Abdominal Pain Due to Hem-o-lok Clip Migration after Laparoscopic Cholecystectomy.   Korean J Gastroenterol. 2018 Dec;72(6):313-317.   doi:10.4166/kjg.2018.72.6.313

[3] Varma, R. and Gupta, J.K. (2004), Failed sterilisation: evidence‐based review and medico‐legal ramifications. BJOG: An International Journal of Obstetrics & Gynaecology, 111: 1322-1332. doi:10.1111/j.1471-0528.2004.00281.x

[4] Kawaguchi Y, Ogawa M, Kawashima Y, Mizukami H, Maruno A, Ito H, Mine T. Risk factors for proximal migration of biliary tube stents. World J Gastroenterol 2014; 20(5): 1318-1324. doi:10.3748/wjg.v20.i5.1318

[5] Güngör, G., & Okur, N. (2016). A Fatal Complication: Intestinal Perforation Secondary to Migration of a Biliary Stent. Polish journal of radiology, 81, 170–172. doi:10.12659/PJR.896231

[6] Ghavidel A. (2015). Migration of clips after laparoscopic cholecystectomy; a case report and literature review. Middle East journal of digestive diseases, 7(1), 45–49.

[7] Delaplace M, Maître F, Dufour T, Landrieux I, Gauthier P, Jebira P, Estève E. (2010). Two cases of cutaneous erythema following spinal cord stimulation. Ann Dermatol Venereol. 137(4):297-300. doi:10.1016/j.annder.2010.02.017

[8] Grubb K, Gagandeep S, Chatzoulis G, Basa N, Palmer S, Correa A, Jabbour N. (2005). Surgical clips: a nidus for foreign body reaction after hepatic resection. Surgical Laparoscopy, Endoscopy & Percutaneous Techniques. 15(6): 363-365. doi:10.1097/

[9] Kalu E, Croucher C, Chandra R. Migrating Filshie clip: an unmentioned complication of female sterilisationBMJ Sexual & Reproductive Health 2006;32:188-189. doi: 10.1783/147118906777888530

[10] Bayar, S., Saxena, R. & Salem, R.R. Foreign body reaction to a metal clip causing a benign bile duct stricture 16 years after open cholecystectomy: Report of a case. Surg Today 30, 534–536 (2000). doi:10.1007/s005950070122

[11] Sahota, P. S., Popp, J. A., Hardisty, J. F., Gopinath, C., & Bouchard, P. (2018). Toxicologic pathology: nonclinical safety assessment. Boca Raton: CRC Press, Taylor & Francis Group.

[12] Komori, K., Kimura, K., Kinoshita, T., Ito, S., Abe, T., Senda, Y., … Shimizu, Y. (2014). Sterile abdominal abscess resulting from remnant laparoscopic clips after sigmoidectomy: A case report and literature review. Asian Journal of Endoscopic Surgery, 7(3), 264–266. doi: 10.1111/ases.12112

[13] Meirow, D., Moses , A., Maayan, S., Schenker, JG. (1989). Chronic tuboovarian abscess due to Staphylococcus aureus: a case report and literature review. Eur J Obstet Gynecol Reprod Biol. 33(3):275-9. doi: 10.1016/0028-2243(89)90142-1

[14] Fink, A.S. Hiatt, J.R., Pitt, H.A., Bennion, R.S., DeSouza, L.R., McCoy, R.D., Meyer, J.H., Thompson, J.E. Jr., Webster, J.L., Wilson, S.E. (1988). Indolent presentation of pancreatic abscess. Experience with 100 cases. Arch. Surg. 123(9):1067-72. doi:10.1001/archsurg.1988.01400330043006

[15] Matthews JB, Gertsch P, Baer HU, Blumgart LH. Hepatic abscess after biliary tract procedures. Surg Gynecol Obstet. 1990;170:469–75.

[16] Doust, B.D., Quiroz, F., Stewart, J.M. Ultrasonic Distinction of Abscesses from Other Intra-abdominal Fluid Collections. (1977). Radiology. 125:1, 213-218. doi:10.1148/125.1.213

[17] Kairys N, Roepke C. Tubo-Ovarian Abscess. [Updated 2019 May 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from:

[18] Uwatoko, T., Tsumoto, T., Wada, N., Urabe, K., Sanbongi, Y., Tokunaga, S., Tsurusaki, Y., & Okada, Y. (2015). Dermatitis caused by metal allergy after coil embolization for unruptured cerebral aneurysm. BMJ case reports, 2015, bcr2015011981. doi:10.1136/bcr-2015-011981

[19] Schalock, P.C., Menné, T., Johansen, J.D., Taylor, J.S., Maibach, H.I., Lidén, C., Bruze, M. and Thyssen, J.P. (2012), Hypersensitivity reactions to metallic implants – diagnostic algorithm and suggested patch test series for clinical use. Contact Dermatitis, 66: 4-19. doi:10.1111/j.1600-0536.2011.01971.x

[20] Hosoki, M., Nishigawa, K., Miyamoto, Y., Ohe, G., & Matsuka, Y. (2016). Allergic contact dermatitis caused by titanium screws and dental implants. Journal of Prosthodontic Research, 60(3), 213–219. doi: 10.1016/j.jpor.2015.12.004

[21] Tackla, R. D., & Ringer, A. J. (2015). Letter to the Editor: Nickel allergy and aneurysm clips. Journal of Neurosurgery, 123(1), 292–293. doi: 10.3171/2014.11.jns142219.

[22] Hannah, J. (2012). Nickel Allergy. What is it and how can it affect our patient care. Gastroenterology Nursing, 35(4), 263–268. doi: 10.1097/sga.0b013e3182603090

[23] Oakley, A. M. M., Ive, F. A., & Carr, M. M. (1987). Skin Clips are Contraindicated when there is Nickel Allergy. Journal of the Royal Society of Medicine, 80(5), 290–291. doi: 10.1177/014107688708000511

[24] Harloff, T., Hönle, W., Holzwarth, U., Bader, R., Thomas, P., & Schuh, A. (2010). Titanium allergy or not? "Impurity" of titanium implant materials. Health, 02(04), 306–310. doi: 10.4236/health.2010.24045

[25] Tamai, K., Mitsumori, M., Fujishiro, S., Kokubo, M., Ooya, N., Nagata, Y., … Inamoto, T. (2001). A case of allergic reaction to surgical metal clips inserted for postoperative boost irradiation in a patient undergoing Breast-conserving therapy. Breast Cancer, 8(1), 90–92. doi: 10.1007/bf02967485

[26] Alexida L, Tiesenga MF (2017) Titanium Staples Allergy in a Middle-Aged Female Patient. Arc Cas Rep CMed 3(3): 144. Available from:

[27] Pacheco, K. A. (2015). Allergy to Surgical Implants. The Journal of Allergy and Clinical Immunology: In Practice, 3(5), 683–695. doi: 10.1016/j.jaip.2015.07.011

[28] Watad, A., Quaresma, M., Bragazzi, N. L., Cervera, R., Tervaert, J. W. C., Amital, H., & Shoenfeld, Y. (2017). The autoimmune/inflammatory syndrome induced by adjuvants (ASIA)/Shoenfeld’s syndrome: descriptive analysis of 300 patients from the international ASIA syndrome registry. Clinical Rheumatology, 37(2), 483–493. doi: 10.1007/s10067-017-3748-9 

[29] Tervaert, J. W. C. (2018). Autoinflammatory/autoimmunity syndrome induced by adjuvants (Shoenfelds syndrome) in patients after a polypropylene mesh implantation. Best Practice & Research Clinical Rheumatology, 32(4), 511–520. doi: 10.1016/j.berh.2019.01.003

[30] Loyo, E., Jara, L. J., López, P. D., & Puig, A. C. (2012). Autoimmunity in connection with a metal implant: a case of autoimmune/autoinflammatory syndrome induced by adjuvants. Autoimmunity Highlights, 4(1), 33–38. doi: 10.1007/s13317-012-0044-1

[31] Stejskal, Vera & Hudecek, Romuald & Stejskal, Jenny & Sterzl, Ivan. (2007). Diagnosis and treatment of metal-induced side-effects. Neuro endocrinology letters. 27 Suppl 1. 7-16. Available from: 

[32] Goehler, L. E., Lyte, M., & Gaykema, R. P. (2007). Infection-induced viscerosensory signals from the gut enhance anxiety: Implications for psychoneuroimmunology. Brain, Behavior, and Immunity, 21(6), 721–726. doi: 10.1016/j.bbi.2007.02.005

[33] Fatemi, S. H. (2005). Neuropsychiatric disorders and infection. London: Taylor & Francis.

[34] Tzeng, N.-S., Chang, H.-A., Chung, C.-H., Kao, Y.-C., Chang, C.-C., Yeh, H.-W., … Chien, W.-C. (2018). Increased Risk of Psychiatric Disorders in Allergic Diseases: A Nationwide, Population-Based, Cohort Study. Frontiers in Psychiatry, 9. doi: 10.3389/fpsyt.2018.00133x

The author is not a medical practitioner and this folder does not constitute medical advice. The folder is general in nature and for informational purposes only. The information presented here is believed to be accurate, but the author makes no warranties regarding its accuracy, and some information may have changed or be outdated. Please consult a qualified medical professional for medical advice.


31 Items